Institutes and Centers

 
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Institute for Systems Genetics

The Institute for Systems Genetics combines research in genome engineering, eukaryotic genetics, and systems biology. We take a systems approach to interrogate the wealth of information available in biology and medicine, and develop innovative technologies, like Big DNA and synthetic Zinc finger proteins, that enable impactful discoveries.

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Center for Human Genetics & Genomics

The Center for Human Genetics & Genomics (CHGG) is a collaborative and diverse group of scientists and physicians focused on advancing our understanding of the human genome, developing new ways to study the function and regulation of the human genome in disease, and working to implement genomic medicine in the NYU Langone Health system.


Labs

 

Beck Lab

We focus on understanding the genetic causes of disease, with an emphasis on inflammatory diseases and their underlying mechanisms.

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Boeke Lab

We study mechanism and genomics of retrotransposition and develop novel tech in genetics, omics and synbio, and we wrote the Sc2.0 yeast genome.

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Aravinda Chakravarti Lab

Deciphering complex genetic disorders with human genetics, genomics, computational biology & animal models.

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Chatterjee Lab

We study how genetic variations lead to cellular changes in diseases of the central and peripheral nervous system focusing on neurocristopathies.

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Davoli Lab

The Davoli Lab applies computational and experimental methods to dissect the causes and consequences of aneuploidy in cancer and human placenta.

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Evrony Lab

We develop new technologies to understand how the genome builds the brain, the origins of brain tumors, and processes of somatic mutation.

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Fenyö Lab

We focus on proteogenomics integrations to understand tumor biology and improve cancer treatment.

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Holt Lab

How does mechanical compression and molecular crowding affect cell biology and drive diseases like cancer, aging and neurodegeneration?

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Lionnet lab

We combine cutting-edge imaging with synthetic biology and modeling to understand the principles of genome organization and transcription regulation.

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Maurano Lab

We develop and implement genomic approaches to investigate gene and chromatin regulation in human development and disease

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Noyes Lab

The Noyes lab has screened over 90 billion protein-DNA interactions to define a code of zinc finger specificity to reprogram transcription factors.

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Ruggles Lab

We focus on understanding cancer, cardiovascular disease and immunology through the application of omics integration and predictive modeling.

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Schluter Lab

We study evolutionary medicine for the microbiome, seeking to understand evolved feedbacks between ecosystems, immune- and nervous system.

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Tsirigos Lab

Our lab uses computational genomics to investigate the role of epigenetics in cancer and machine learning to develop models of response to therapy.

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Yanai Lab

We study cellular states during tumorigenesis and infection using a computational and systems approach with single-cell and spatial transcriptomics.

 
 

Join us

Faculty Positions

The Institute for Systems Genetics is currently accepting applications for assistant and associate level faculty positions for our new SynBioMed Center. Please see here for details.

Trainee Positions

Current NYUGSoM Stipend Levels - $45,890 for Graduate Students and $58,500 for Postdoctoral Fellows.

Graduate Students - Boeke Lab

The Boeke Lab accepts NYULH graduate students through the Vilcek Institute of Graduate Biomedical Sciences. Related programs include: Systems & Computational Biomedicine, Stem Cell Biology, and Developmental Genetics. We also participate in the Department of Biomedical Engineering PhD program at NYU Tandon School of Engineering. Interested Vilcek students should contact Jef Boeke once they are accepted to NYU; BME students should contact him as part of the process of applying to the Tandon PhD program.

Graduate Students and Postdoctoral Fellow - Davoli Lab

The Davoli Lab applies computational and experimental methods to dissect the causes and consequences of aneuploidy in cancer and human placenta. We are looking for highly motivated scientists with great communication skills, a collaborative spirit and love for science. Postdoctoral positions are available for a wet-lab project, a dry-lab project or a combination of both. To apply, please send a brief letter of interest and a CV to Teresa Davoli.

Graduate Students and Postdoctoral Fellows - Evrony Lab

The Evrony lab is looking for intrepid graduate students and postdoctoral fellows to develop new single-cell genomics approaches for studying brain development, the origins of brain tumors, and somatic mutation processes. To apply, send a brief letter of interest and a CV to Gilad Evrony.

Graduate Students and Postdoctoral Fellows - Fenyö Lab

The Fenyö lab focuses on proteogenomics integration to better understand tumor biology and improve cancer treatment. We are looking for highly motivated scientists interested in developing and applying computational methods to analyze biomedical data. To apply, send a brief letter of interest and a CV to David Fenyö.

Graduate Students and Postdoctoral Fellows - Holt Lab

The Holt Lab is interested in hearing ideas you’re excited about. Take a look at our specific project areas and use the contact form here for any inquiries.

Graduate Students and Postdoctoral Fellows - Lionnet Lab

The Lionnet lab is looking to bring together a diverse group of creative scientists with backgrounds ranging from imaging, genomics, cell biology, tool building, to computation and theory. We maintain a supportive and collaborative culture. Interested? Contact Timothée Lionnet. We accept NYULH graduate students through the Vilcek Institute of Graduate Biomedical Sciences. Related programs include: Systems & Computational Biomedicine, Cell Biology, Biochemistry and Molecular Biophysics and Developmental Genetics; motivated students from other programs are encouraged to reach out as well. We also participate in the Department of Biomedical Engineering PhD program at NYU Tandon School of Engineering. Interested Vilcek students should contact Timothee Lionnet once they are accepted to NYU; BME students should contact him as part of the process of applying to the Tandon PhD program.

Graduate Students and Postdoctoral Fellows - Maurano Lab

The Maurano lab is always looking for talented Fellows to join our group. Candidates with both experimental and computational experience are welcome. Undergraduate or Masters students majoring in technical fields should contact us regarding internship possibilities during the school year or the summer. We accept NYULH graduate students through the Vilcek Institute of Graduate Biomedical Sciences. To apply, please contact Matthew Maurano.

Graduate Students and Postdoctoral Fellows - Noyes Lab

The Noyes Lab is interested in how proteins interact with their targets from structural, computational and cell biology perspectives. As such, our primary goals involve developing new tools to sample these interactions as comprehensively as possible. We are currently in a big state of transition as we have recently developed a technique to reprogram transcription factors. This has opened up several avenues of research and is a very exciting time. Read more here about potential projects. To apply, please contact Marcus Noyes.

Postdoctoral Fellow - Jef Boeke & Teresa Davoli’s Labs

Postdoctoral position is available for a wet-lab project on genome engineering that may also involve some dry-lab aspects. Candidates with a background in genetics/molecular biology/stem cell biology and genome engineering in cells or tissues are encouraged to apply. The Postdoctoral Researcher will have the opportunity to receive training on the use of state-of-the-art approaches in synthetic genetics and genomics analyses. We are looking for highly motivated scientists with great communication skills, collaborative spirit and a love for science. The project will mainly focus on genome engineering of chicken cells to build sex selective progeny. To apply, please contact Teresa Davoli.

Postdoctoral Fellow - Aravinda Chakravarti Lab

The Aravinda Chakravarti Lab seeks a postdoctoral fellow to investigate the genetic and functional dissection of Hirschsprung disease, a multifactorial disorder of the enteric nervous system resulting from failure of intestinal innervation. To apply or to obtain more information about the position, email Aravinda Chakravarti.

Postdoctoral Fellow - Aravinda Chakravarti Lab

The Aravinda Chakravarti laboratory at NYU School of Medicine’s Center for Human Genetics and Genomics has recently been funded on a major project to understand the genetic basis of sex differences in autism in, collaboration with the laboratories of Evan Eichler, Huda Zoghbi and Tom Nowakowski. We seek a postdoctoral fellow at NYUGSoM to analyze whole genome sequence and brain transcriptomic, open chromatin and sex-hormone-dependent gene expression data, from patients and reference samples, for deciphering the sex-specific and sex-independent brain regulatory machinery in autism. We expect candidates to have significant training in human genetics, genomics, computational biology and/or computer science with a proven ability of independent research in a collaborative project. The applicant should have an abiding interest in understanding the genetic mechanisms in complex disease. To apply email Aravinda Chakravarti with your resume, publication list and a one page narrative of your research interests and accomplishments. For more information about our lab see here.

Staff Positions

Research Associate - Maurano Lab
We are looking for a skilled, motivated Research Associate to join our synthetic regulatory genomics team, which is using cutting-edge synthetic DNA, genomics and genome engineering techniques to understand the regulatory architecture of genomic loci involved in human traits and diseases. Candidates must have an undergraduate degree in the biological sciences and past experience in a research setting. This position involves basic molecular techniques including PCR, DNA/RNA sample preparation, basic mammalian tissue culture, and genomics techniques including Illumina sequencing. For more info, see our lab website at http://mauranolab.org/. Candidates should send their CV to Matthew Maurano at: maurano@nyu.edu.

Associate Research Technician - Center for Human Genetics and Genomics

We have an exciting opportunity to join our team as a Associate Research Technician. The successful candidate will join a laboratory developing and utilizing cutting-edge, high throughput genetic, functional genomic and computational technologies for dissection of complex genetic diseases, and expected to perform routine genetic analyses in this research laboratory on a number of human disease projects and working with mouse models of human disease.  Learn more and apply here.

Associate Bioinformatics Programmer - Chakravarti Lab
The Associate Bioinformatics Programmer is a critical member of Dr. Aravinda Chakravarti’s lab and will perform intensive analysis of human genome genotype and sequence data for gene discovery in complex human disease. The individual will adapt existing and develop novel software applications for a growing computing and analysis development team in human disease genomics; work collaboratively with other lab members, but also complete projects on time and independently; and develop computational expertise in genetics. Learn more and apply here.